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MiniBooNE is a big spherical mineral oil detector that is designed to see nue and numu neutrino interactions.
Nus interact infrequently, but when they do, we see their effect indirectly because of the muon (in the case of a numu), electron ( for nue), pions, or from ejected or excited nucleii.
It has been discovered that neutrinos will actually change from one flavor into another. This is called neutrino oscillation, and is directly related to the question of neutrino mass.